Vacancy -Research Scientist
Antibody Discovery (Protein Sciences)
The RxCelerate group of companies provides a platform for out-sourced drug discovery and development services and has a client base ranging from virtual biotech companies to some of the top 15 global pharmaceutical companies. We design and deliver complete drug development programmes from inception through to and including Phase II clinical studies. RxBiologics is a subsidiary of RxCelerate with a focus on delivery of biologics drug discovery. Our aim is to become the antibody drug developer of choice for the UK’s venture backed biotech start-ups and outsourced pharma projects.
RxBiologics has an excellent opportunity for an enthusiastic and motivated scientist to join us and help expand our services to support our growing client base. The position is based within the RxBiologics team, working at the Babraham Research Campus, a leading site within the Cambridge biotechnology hub.
The Role
The successful candidate will join our team of scientists supporting client antibody drug discovery programmes and internal technical development. They will primarily develop and perform assays for antibody isolation and characterisation but will additionally provide support in phage display selections and protein expression/purification when required. A strong interest in antibody drug discovery, proactive approach and motivation to learn is key for this position. RxBiologics will provide practical training in antibody discovery processes and techniques. This is a full-time lab-based role, and the candidate will report into a senior member of the team.
Main Responsibilities
- Design and generation of protein expression constructs.
- Application of molecular biology techniques including cloning and sequence analysis.
- Routine expression and purification of antibodies/antibody fragments.
- Production and QC of recombinant proteins to support antibody discovery campaigns.
- Performing antibody/protein characterisation assays e.g. ELISA, affinity determination.
- Provision of cross-functional support under supervision.
- Analysis and interpretation of data.
- Maintenance of accurate experimental records and delivery of high-quality reports.
- Assist with general laboratory duties.
Essential Skills / Requirements
- PhD (or equivalent) in a relevant biological science and preferably at least a year’s laboratory-based experience gained within the biotechnology or pharmaceutical sector.
- Skilled in molecular biology techniques such as nucleic acid preparation, PCR, cloning and sequence analysis.
- Experience of protein expression using bacterial and mammalian systems.
- Experience of protein purification and characterisation (e.g. SDS PAGE, western blotting and SEC analysis).
- Knowledge of plate-based immunoassays (ELISA) and affinity determination methods such as SPR.
- Ability to conduct experiments following standard protocols and accurately interpret data.
- Excellent organisational skills, capable of delivering to tight deadlines.
- Good interpersonal and communication skills with ability to work effectively in a team.
RxBiologics offers a competitive salary with an annual bonus scheme and company benefit package.
When applying for this role, please include a cover letter outlining how you meet the competencies described above. Applicants should send their cover letter and curriculum vitae in PDF format to [email protected] by 22nd June 2022. Informal enquiries can also be directed to this email address.
Only applicants based in the UK and EU need apply, as this role does not qualify for international sponsorship.
Advanced small molecule and protein design services using our state-of-the-art ProtoDiscovery™ computational platform.
Get in touch
Call Us 01223 839557
Email Us [email protected]
Visit Us
Dorothy Hodgkin Building,
Babraham Research Campus,
Babraham, Cambridge CB22 3FH